Note: This article applies only to the MetaTrader 5 platform. If you're using MetaTrader 4, this information may not be relevant.
No — only MT5-compatible Expert Advisors can be used on the MetaTrader 5 platform.
MT4 EAs are built using MQL4, while MT5 uses a different language called MQL5. These two programming languages have different structures and are not cross-compatible. As a result, an EA designed for MT4 cannot run on MT5.